AI Agent is undoubtedly the central theme of the current on-chain market. From infrastructure construction, tool development, and DeFi to gaming and other products, the rapid iteration of AI Agents is driving explosive market growth, commanding attention and capturing users’ minds. Recently, the continuous rise in the trading volume share of DEX/CEX has proven the intense competition for on-chain liquidity and attention, with market capital flow undergoing structural changes. According to data from The Block and DeFiLlama, the spot trading volume share of DEX and CEX has significantly increased in recent months. As of January 2025, this ratio has reached 20.2%, setting a new all-time high. In this trend, many non-AI crypto projects lacking favorable narratives are also speeding up to join in, hoping to ride the wave of AI Agent, which comes with its own built-in traffic. This article from PANews organizes 22 crypto projects laying out AI Agent frameworks, covering various sectors such as gaming, public chains, payments, DeFi, and DePIN. These projects are mainly accelerating the construction and development of the AI Agent ecosystem through technical frameworks and the implementation of use cases.

Illuvium: Introducing Autonomous AI NPCs to Gaming

Illuvium is an RPG and NFT game built on Ethereum. On January 7, Illuvium announced a partnership with Virtuals Protocol to enhance the gaming experience of the upcoming Illuvium MMO Lite. This collaboration will utilize Virtuals’ AI technology and its G.A.M.E LLM framework to provide dynamic and intelligent behavior for NPCs, offering players an immersive experience.

Story Protocol: High-Paid Hire of AI Agent Luna

Story Protocol is a Layer1 designed specifically for intellectual property (IP). In December of last year, after releasing a TCP/IP framework for AI Agents, Story Protocol announced, “The human intern requested time off and plans to hire an AI Agent to manage Twitter.” They ultimately decided to hire Luna to manage their X account, offering a salary of 36.5 USDC annually, claiming she would bring “charm, personality, and a bit of mischief.”

Circle: Exploring AI Agents Using USDC for Independent Operations and Trading

In the second half of 2024, Circle announced a partnership with Solana to launch AI agents to enhance infrastructure security. In November of the same year, Circle released a report stating that the company had issued over $2 billion worth of USDC in the past few weeks, exploring how the combination of artificial intelligence and blockchain technology could change people’s understanding of work and finance, especially through the use of “autonomous” payments. Circle introduced the concept of AI agents using USDC to operate and trade independently. Additionally, they built a sample application to “demonstrate the autonomous system” and encouraged users to use this template to build their own projects and provide feedback.

Arbitrum: Launching a Grant Program and Building AI Agent Partnerships

In November 2024, Arbitrum announced the launch of a $1 million Trailblazer grant program aimed at attracting developers with innovative ideas to deploy impactful AI Agents or other AI products based on Arbitrum. Arbitrum also formed partnerships with Eilza Labs and ARC Agents.

Stripe: Planning to Launch an AI Agent Toolkit

In November 2024, Stripe’s product lead Jeff Weinstein stated that they were launching a software development toolkit (SDK) specifically built for AI agents. This toolkit supports API calls for payments, billing, issuance, and more through large language models (LLM), integrating platforms like Vercel, LangChainAI, and CrewAIInc, allowing users to work with any model through functions.

Coinbase: Releasing Multiple AI Agent Products to Simplify On-Chain Operations and Interactions

At the end of October last year, Coinbase launched a new tool, Based Agent, developed using Coinbase SDK, OpenAI, and Replit platforms. This tool allows users to create AI agents with crypto wallet functionality in just 3 minutes, capable of executing on-chain transactions, token swaps, staking, and other tasks. The following month, Coinbase’s developer platform also launched a framework called AgentKit in collaboration with Langchain for building AI agents. It integrates on-chain (Base chain) and off-chain interaction capabilities, combining Web2 APIs and on-chain data, enabling agents to autonomously browse content and execute on-chain operations.

Orca: Developing an AI Agent Version of an Automated Bot

Orca is an AMM DEX on Solana. On January 6, ai16z co-founder Shaw revealed in an interview with BlockBeats that ai16z is collaborating with Orca to develop an automated bot for managing Orca’s liquidity pools. Users simply need to deposit tokens, and if the pool does not exist, the bot will automatically create a new one. If the pool already exists, it will place the tokens into the existing pool. It will then continuously monitor these pools and withdraw tokens automatically if it detects situations that could lead to permanent loss, such as token price divergence. Users can also program token price differences or adjust token pairing methods.

io.net: Establishing Multiple Collaborations in the AI Agent Field

DePIN leader project io.net has established several collaborations in the AI Agent field. For example, in December last year, io.net announced a partnership with autonomous AI agent Zerebro to enhance Ethereum validation operations. Additionally, io.net collaborated with ai16z to provide decentralized GPU computing power to support the latter’s model operations.

IoTeX: Launching the First AI Agent in the DePIN Field, BinoAI

IoTeX is an open platform for building AI + DePIN infrastructure in a modular fashion. In December last year, IoTeX announced the launch of the first AI agent in the DePIN field: BinoAI. Built on the ELIZA-OS framework, BinoAI aims to establish a foundation for decentralized autonomous evolution in the DePIN space. BinoAI will autonomously learn through AI, gain insights into DePIN-related knowledge, and securely access and interact with on-chain data, based on ai16z’s ELIZA framework. Combined with IoTeX’s decentralized DePIN module infrastructure, BinoAI will operate in a fully decentralized, trustless environment, with use cases in smart travel, energy systems, smart wearables, and smart homes in the DePIN space.

Smolverse: Developing an AI Pet Game Based on Eliza

Smolverse is a game and NFT project on Treasure DAO. Since December of last year, Smolverse has partnered with ai16z to develop an on-chain AI Tamagotchi game called “Smolworld,” which integrates Eliza’s Agent framework.

Phala Network: Building an Eliza-Based TEE Framework

Phala Network, formerly the privacy computing infrastructure of the Polkadot ecosystem, has partnered with a16z to build Eliza’s TEE (Trusted Execution Environment) framework. This integration adds TEE technology into Eliza’s multi-agent framework, providing cryptographic verifiability and enhanced privacy to ensure secure and reliable interactions. Notably, projects like Spore.fun and aiPool have utilized Phala Network’s TEE technology.

Injective: Launching the First Cross-Chain AI Agents Hub

Injective is an interoperable Layer 1 blockchain. Recently, Injective announced a collaboration with Sonic SVM, the first SVM blockchain on Solana, to launch the first cross-chain AI agent platform, Smart Agent Hub. This platform will provide developers with powerful tools and frameworks to create, manage, and monetize AI agents, facilitate cross-chain asset transfers, and deliver a unified development experience. The first testnet is expected to launch in Q1 2025, and the ecosystem will gradually expand into gaming, entertainment, DeFi, and social platforms like TikTok and Web3 gaming.

Fuel: Launching the AI Agent Toolkit Fuel Agent Kit

Fuel is a modular execution layer designed for the Ethereum Rollup ecosystem. Recently, Fuel announced the launch of the AI agent toolkit, Fuel Agent Kit. This toolkit will connect users’ AI agents to various applications on Fuel or allow users to build new AI agents using Fuel.

Gaia: Creating Custom AI Agents

Gaia is a decentralized open-source AI infrastructure platform. In November of last year, Gaia announced a collaboration with the AI platform Vana to create powerful and custom AI agents. Currently, Gaia’s AI agents are integrated with projects like EigenLayer and ENS.

Aethir: Incubating and Investing in AI Agents

Aethir is a decentralized real-time rendering network. In recent months, Aethir has continued to incubate and invest in AI agents. For example, at the end of last year, it announced the third round (Batch 3) of its $100 million ecosystem fund, focusing on the integration of gaming and AI agents. Additionally, Aethir provides free GPU computing power to Eliza agent developers.

DWF Labs: Developing AI Agent Trading and Establishing a Fund for Support

DWF Labs has successfully managed its investment portfolio autonomously through the development of AI trading agents, which have already been integrated into DWF’s trading system workflow. At the end of last year, DWF Labs also announced the establishment of a $20 million fund to support the development of autonomous AI agents, with projects like TAO Cat and HeyAnon receiving funding.

Blade Games: Integrating AI Agents into the On-Chain Gaming Ecosystem

Blade Games is one of the largest on-chain gaming ecosystems on Arbitrum and Mantle, attracting over 850,000 registered users. Blade Games combines on-chain gaming with AI agent technology, built on the zkVM stack. Players on this platform can play games, train AI agents, and create their own on-chain economy.

aelf: Launching the No-Code AI Agent Framework aevatar intelligence

In December 2024, Layer 1 blockchain aelf announced the launch of the no-code AI agent framework, aevatar intelligence. This framework is supported by multiple large language models (LLMs), allowing external developers to integrate their preferred LLMs, creating a collaborative ecosystem that drives innovation and expands the framework’s functionality. The first use case, AI pump pad, is set to launch in early January 2025.

SendAI: Enabling Autonomous AI Agent Execution of Solana On-Chain Operations

SendAI is an accelerator for the Solana AI ecosystem. In December 2024, SendAI announced the release of the open-source toolkit, Solana Agent Kit, which supports any AI model to autonomously execute Solana on-chain operations. It has integrated with mainstream protocols such as Jupiter, Metaplex, and Raydium. The toolkit uses LangChain technology and supports AI models from GPT-4 to Llama, with plans to integrate with frameworks such as ai16z’s Eliza and Zerebro’s ZerePy.

Artela: Launching the Next-Generation Full-Chain AI Agent Technology Framework

In December 2024, the parallel EVM public chain Artela Network officially launched its full-chain AI Agents technology framework. Based on Artela’s on-chain intelligence, decentralized trusted execution, and flexible block space, this framework solves the pain point of AI Agents relying on centralized servers for autonomy. It provides AI Agents with true “read, write, and own” capabilities.

Frax: Developing the AI Agent Technology Stack “AIVM” for Blockchain

In mid-December 2024, decentralized stablecoin protocol Frax Finance announced its collaboration with the related project IQ to develop an AI technology stack called “AIVM.” This stack is based on the Fraxtal internal parallel blockchain developed under the Layer2 rollup protocol and allows AI agents to operate fully autonomously, without a single control point, ultimately enabling seamless collaboration between AI and blockchain.

Planet Mojo: Launching the AI Agent Mr. WWA, First Game Coming Soon

Planet Mojo is a GameFi game developed on the Magic platform with a PVP auto-chess genre. On January 7, Planet Mojo announced its collaboration with Virtuals to launch the AI Agent Mr. WWA (Winston Wylde Alexande), with the WWA token serving as the platform’s reward token. The foundation will support continuous buybacks. Additionally, Planet Mojo’s first game, Agents of Poker, is set to launch soon.

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